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Application · Drug delivery

Silicone for drug delivery & drug-eluting devices

Silicone is a workhorse matrix for controlled and sustained drug release — implants, intravaginal/ophthalmic devices and drug-device combination products — because release rate can be tuned through the polymer and geometry. The two things to get right: cure-system / API compatibility (some APIs and excipients inhibit platinum (addition) cure, so grade and cure choice matter), and compliance grade by contact duration (restricted vs unrestricted). BIO supplies NuSil / Avantor grades with selection and cure-compatibility guidance.

Solution essentials

  • Release tuning: release rate is set by the silicone matrix and device geometry; pick the polymer for the target profile.
  • Cure compatibility: some APIs/excipients inhibit platinum cure — validate cure with your formulation, or select a compatible grade/cure system.
  • Compliance: long-term implantable → unrestricted; choose by contact type and duration; ISO 10993 / documentation per device.
  • Combination products: align material documentation with your drug-device regulatory pathway (master-file references where available).

What BIO provides

BIO provides selection, cure-compatibility advice, documentation and supply of NuSil / Avantor silicone for China drug-device combination teams.

FAQ

Why is silicone used for drug delivery?

Its permeability and tunable matrix allow controlled, sustained release; release rate is set by the silicone and device geometry, making it well suited to long-term implants and combination products.

Will my drug interfere with silicone cure?

It can — some APIs and excipients inhibit platinum (addition) cure. Validate cure with your actual formulation; if needed, select a compatible grade or cure system.

Restricted or unrestricted grade?

By contact type and duration — long-term implantable devices need unrestricted implant-grade silicone with ISO 10993 device-level evaluation.

What can BIO support?

Selection, cure-compatibility guidance, documentation and supply of NuSil / Avantor grades. Contact [email protected] / +86-21-6054-7148.

Need exact grade selection and a quote for your device and annual volume? Talk to a BIO engineer ([email protected] / +86-21-6054-7148), or browse medical silicone by type.

Tell us your device — we return the grade and the paperwork.

Genuine NuSil / Avantor medical-grade silicone, matched to your application, with TDS / CoA and lot-level traceability.

Get selection / quote