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Industry Insights · Medical Polymers & Silicone

Choosing a silicone cure system: platinum / peroxide / condensation

The cure system decides whether a silicone can be formed in your process, how much it shrinks, whether it leaves byproducts and whether it needs a post-cure. Know the three families before you choose.

2026-06-17BIO Industry Insights

Comparison diagram of three silicone cure systems
Three silicone cure families: addition (platinum-catalyzed, no byproducts), peroxide (free-radical, needs post-cure), condensation (moisture-cured, one-part). Illustrative.
In short: Silicone has three cure families: platinum addition — no byproducts, <1% shrinkage, cures thick sections, fast with heat; the first choice for medical and precision parts, but sensitive to amines/sulfur/organotin/some drugs that can 'poison' (inhibit) it. Peroxide — free-radical crosslinking, 2–5% shrinkage, needs a post-cure to remove byproducts; common for HCR extrusion/transfer molding. Condensation (tin RTV) — moisture-cured, one-part no-mix, near-indefinite work time, but slow, with acid/oxime byproducts and limited to thin sections.

All three at a glance

The table summarizes the key differences (training-level overview; verify cure schedules against product TDS):

PropertyAddition (Pt)PeroxideCondensation
MechanismCatalytic additionFree radicalMoisture-dependent
ByproductsNoneAcid or alcoholAcid or oxime
Shrinkage<1%2–5%2–5%
Post-cureOptionalRequiredOptional
Thick sectionsExcellentLimitedLimited
Work timeAdjustableLongHours to indefinite
CostHigherLowerLower

Why platinum cure gets 'poisoned'

  • Amines, sulfur, organotin and some drug-containing/nitrogen-bearing formulations inhibit platinum catalysis, causing no cure or incomplete cure;
  • Mitigate: test compatibility before scaling / increase platinum loading / switch to tin condensation or peroxide (especially for amine-containing drugs).

How to choose: by scenario

  • Medical implants, precision thick parts, low shrinkage → platinum addition;
  • HCR extruded tubing/profiles, transfer molding → peroxide (mind the post-cure);
  • One-part no-mix, self-leveling seals/coatings on thin sections → condensation RTV;
  • Drug delivery (DDS) → depends on the drug: clean drugs can use platinum; amine-containing drugs favor tin condensation or peroxide, tested formulation-by-formulation.

The BIO angle

Choosing a grade is really choosing a combination of form + cure + class. BIO helps you lock the cure system from your process and device, match the right NuSil MED grade, flag platinum-poisoning risk and compatibility testing, and provide the TDS.

FAQ

Which cure is most common for medical devices?

Platinum addition: no byproducts, low shrinkage, cures thick sections, fast with heat, long implant history.

What 'poisons' platinum cure?

Amines, sulfur, organotin and some drug/nitrogen-bearing substances inhibit platinum; do compatibility testing or switch cure systems.

Why does peroxide cure need a post-cure?

To remove decomposition byproducts (acids, etc.) and stabilize properties; common for HCR extruded parts.

What is condensation cure good for?

One-part no-mix, self-leveling seals/coatings on thin sections; not for thick parts (moisture cannot reach the core).

Which cure for drug-eluting (DDS) products?

Depends on the drug: clean drugs can use platinum; amine-containing drugs tend to inhibit platinum, favoring tin condensation or peroxide, tested per formulation.

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Note: an original analysis compiled from public industry information; figures and conclusions per official/original sources. Not investment advice.

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